Variant | Gene | Disease | Risk Allele | Score vda | Association Type | Original DB | Sentence supporting the association | PMID | PMID Year | ||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
|
T | 0.800 | CausalMutation | CLINVAR | Mutation and phenotypic spectrum in patients with cardio-facio-cutaneous and Costello syndrome. | 18042262 | 2008 |
|||||||
|
|
G | 0.800 | CausalMutation | CLINVAR | ||||||||||
|
|
T | 0.800 | CausalMutation | CLINVAR | Germline KRAS and BRAF mutations in cardio-facio-cutaneous syndrome. | 16474404 | 2006 |
|||||||
|
|
A | 0.720 | CausalMutation | CLINVAR | Mutations of the BRAF gene in human cancer. | 12068308 | 2002 |
|||||||
|
|
G | 0.720 | CausalMutation | CLINVAR | Mutations of the BRAF gene in human cancer. | 12068308 | 2002 |
|||||||
|
|
T | 0.700 | CausalMutation | CLINVAR | Clinical biomarkers in oncology: focus on colorectal cancer. | 19537845 | 2009 |
|||||||
|
|
T | 0.700 | CausalMutation | CLINVAR | ||||||||||
|
|
T | 0.700 | CausalMutation | CLINVAR | ||||||||||
|
|
G | 0.700 | CausalMutation | CLINVAR | Missense mutations of the BRAF gene in human lung adenocarcinoma. | 12460919 | 2002 |
|||||||
|
|
G | 0.700 | CausalMutation | CLINVAR | Identifying recurrent mutations in cancer reveals widespread lineage diversity and mutational specificity. | 26619011 | 2016 |
|||||||
|
|
T | 0.700 | CausalMutation | CLINVAR | Mutations of the BRAF gene in human cancer. | 12068308 | 2002 |
|||||||
|
|
G | 0.700 | CausalMutation | CLINVAR | Genetic predictors of MEK dependence in non-small cell lung cancer. | 19010912 | 2008 |
|||||||
|
|
A | 0.700 | CausalMutation | CLINVAR | Mutations of the BRAF gene in human cancer. | 12068308 | 2002 |
|||||||
|
|
G | 0.700 | CausalMutation | CLINVAR | Prognostic vs predictive molecular biomarkers in colorectal cancer: is KRAS and BRAF wild type status required for anti-EGFR therapy? | 21129611 | 2010 |
|||||||
|
|
T | 0.700 | CausalMutation | CLINVAR | Prognostic and predictive biomarkers in resected colon cancer: current status and future perspectives for integrating genomics into biomarker discovery. | 20350999 | 2010 |
|||||||
|
|
T | 0.700 | CausalMutation | CLINVAR | ||||||||||
|
|
G | 0.700 | CausalMutation | CLINVAR | Kinase-impaired BRAF mutations in lung cancer confer sensitivity to dasatinib. | 22649091 | 2012 |
|||||||
|
|
T | 0.700 | CausalMutation | CLINVAR | ||||||||||
|
|
A | 0.700 | CausalMutation | CLINVAR | The road to resistance: EGFR mutation and cetuximab. | 22310681 | 2012 |
|||||||
|
|
T | 0.700 | CausalMutation | CLINVAR | ||||||||||
|
|
T | 0.700 | CausalMutation | CLINVAR | ||||||||||
|
|
T | 0.700 | CausalMutation | CLINVAR | ||||||||||
|
|
G | 0.700 | CausalMutation | CLINVAR | Rapid identification of somatic mutations in colorectal and breast cancer tissues using mismatch repair detection (MRD). | 18186519 | 2008 |
|||||||
|
|
T | 0.700 | CausalMutation | CLINVAR | ||||||||||
|
|
T | 0.700 | CausalMutation | CLINVAR |